New FDA guidance on the use of Bayesian statistics signals a broader shift in accommodating more flexible clinical trial ...

Bayesian approaches to statistical inference combine prior beliefs with observed data through a likelihood function to yield a posterior distribution, offering a coherent framework for uncertainty ...

Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study We divided the borrowing ...

Industry groups and drugmakers want the US Food and Drug Administration (FDA) to explicitly clarify that Bayesian statistical methods can be used for products beyond those intended for children and ...

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...