† Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322. United States ¶ Department of Biochemistry, Emory University, 1510 Clifton Rd., Atlanta, Georgia 30322, United ...

Circular arrangement is one of the interesting topics of Permutations. Before understanding circular arrangement let us review some important concepts of linear permutation. In linear arrangement n ...

The ability to design and build nonnative DNA sequences conferring specific and useful engineered functions on cells defines the field of synthetic biology. Here, we describe a synthetic biology ...

Although naturally occurring proteins form stable defined tertiary structures, it is well known that many proteins with non-natural sequences have unstructured conformations 1,2. This suggests that ...

Circular permutations usually retain the native structure and function of a protein while inevitably perturbing its folding dynamics. By using simulations with a structure-based model and a rigorous ...

Abstract: We consider the problem of sorting a circular permutation by super short reversals (i.e., reversals of length at most 2), a problem that finds application in comparative genomics. Polynomial ...

Imagining that protein stability needs to be kept within some limits for biological function is easy. However, is there any corresponding pressure on protein folding and, hence, the dynamic ...

Add a description, image, and links to the circular-permutation topic page so that developers can more easily learn about it.