The complement cascade, traditionally appreciated for its role in innate immunity, has emerged as a pivotal regulator of bone repair. Activation of complement components generates anaphylatoxins such ...

Researchers have identified mutations in a set of proteins that predispose their carriers to preeclampsia, a complication that shows up in between 5 percent and 10 percent of pregnancies. Their work ...

Allergic asthma is driven by a complex interplay between innate and adaptive immunity in which the complement system plays a central role. Activation of complement via the classical, lectin or ...

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function. The advent of severe acute ...