The humoral complement system in humans has important roles in tissue homeostasis and immune protection against infectious agents 1,2. A central and pivotal step in the complement response is ...

Treatment-related toxicity remains a challenge in pediatric hematopoietic stem cell transplantation (HSCT). In this prospective, single-center study we studied activation of the complement system peri ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

Priority review for ravulizumab in IgA nephropathy could establish the first C5 complement inhibitor label in this indication, addressing substantial residual progression risk despite current standard ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...