Computational trajectory analysis is a key computational task for inferring differentiation trees from this single-cell data. An open challenge is the prediction of complex and multi-branching trees ...

In a screening for a functional impact to the neuronal differentiation process, researchers identified a specific circular RNA, circZNF827, which surprisingly 'taps the brake' on neurogenesis. The ...

Impaired neuronal differentiation is a feature of neuroblastoma tumorigenesis, and the differentiation grade of neuroblastoma tumors is associated with patient prognosis. Detailed understanding of the ...