In multicellular organisms, each cell is influenced by the others in its surrounding environment, and the maintenance of cellular and tissue spatiality – or lack thereof – carries significant ...

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

A collaborative project has created a comprehensive guide to help standardize spatial transcriptomics practices. Spatial transcriptomics provides a unique perspective on the genes that cells express ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

Perturb-FISH aims to address both challenges. Because this technique harnesses imaging spatial transcriptomics (iST), it offers high resolution and scalability, as ...

LatchBio provides white-labeled data infrastructure, analysis tools and delivery portals for kit, instrument, and solution providers. Today, LatchBio released a 25 million cell spatial atlas spanning ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...