Scientists at the Texas A&M University College of Medicine have made a breakthrough discovery about the development of the brain. This new information contributes to our understanding of how the part ...

Translation modulates the timing and amplification of gene expression after transcription. Brain development requires uniquely complex gene expression patterns, but large-scale measurements of ...

In a recent study published in Science, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans. Study: Human TKTL1 implies ...

Basal radial glial cells generate the majority of the neurons in the developing neocortex, a part of the brain that is crucial for many cognitive abilities. As TKTL1 activity is particularly high in ...

The question of what makes modern humans unique has long been a driving force for researchers. Comparisons with our closest relatives, the Neandertals, therefore provide fascinating insights. The ...

The expansion of the human brain during evolution, specifically of the neocortex, is linked to our cognitive abilities such as reasoning and language. A certain gene called ARHGAP11B that is only ...

Neanderthals are the closest relatives to modern humans. Comparisons with them can therefore provide fascinating insights into what makes present-day humans unique, for example regarding the ...

The human neocortex, the evolutionarily youngest part of the cerebral cortex, is about three times bigger than that of our closest relative, the chimpanzee. In order to fit inside the restricted space ...

A human-specific gene causes a larger neocortex in the common marmoset, a non-human primate. A human-specific gene causes a larger neocortex in the common marmoset, a non-human primate. The expansion ...