Nature

A targeted next-generation sequencing panel for identification of clinically relevant mutation profiles in solid tumours

Classic histo-morphological diagnosis by immunohistochemistry and fluorescence in-situ hybridization is undoubtedly the gold standard in pathology. However, it is often necessary to characterize a ...
Nature

Metagenomic next-generation sequencing for concurrent diagnosis of infections and malignancies in patients with lung lesions: a single-center prospective study

Metagenomic next-generation sequencing (mNGS) offers sensitive and rapid pathogen detection and has the added advantage of analyzing chromosomal copy number variations (CNVs) of the host in the same ...
ascopubs.org

Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based Circulating Tumor DNA Assays, Version 2.0

Human Epidermal Growth Factor Receptor 2 Quantification Using Computational Pathology to Identify Novel Biomarkers for Trastuzumab Deruxtecan–Treated Human Epidermal Growth Factor Receptor 2–Positive ...
Business Wire

Meridian Bioscience and 4bases Announce Collaboration to Enable Rapid, Globally Scalable Next-Generation Sequencing Workflows

Ambient-stable NGS workflows, enabled by Meridian’s lyophilization expertise, expand global access to 4bases’ KaryoSolver™*, a platform for rapid structural variant analysis CINCINNATI--(BUSINESS WIRE ...
RAPS

FDA drafts guidance on using next-generation sequencing to assess gene therapy safety

The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing (NGS) methods in nonclinical studies to assess the safety risks associated ...