Although Mendelian randomization techniques can involve fairly computationally intensive analyses, the fundamental principles that guide these study designs are straightforward and if understood ...

While randomization is required by regulatory bodies, it is up to the sponsor on how to conduct it. Developing a clinical trial’s effective monitoring plan can be overwhelming. The FDA acknowledges ...

Ensuring patient safety is paramount in the development of new pharmaceutical products, which, while beneficial, can also pose potential risks. Traditional methods for analyzing safety data have been ...

The rdlocrand package implements estimation, inference, and graphical procedures for Regression Discontinuity (RD) designs using local randomization methods. Cattaneo, Frandsen and Titiunik (2015): ...

Fractional factorial designs are a type of factorial designs, where you test the effects of multiple factors and their interactions on a response variable. However, unlike full factorial designs, ...

Randomization and Trial Supply Management (RTSM), also known as IRT (Interactive Response Technology), has become a critical component of modern clinical trials. In 2026, with increasingly complex ...