Pyrosequencing technique is based on sequencing-by-synthesis principle. The method is based on the sequencing of single stranded DNA and now-a-days sequencing of double stranded DNA is also possible.

Commercial DNA sequencers were first produced in the late 1990s. They have been named second-generation or next-generation sequencers to distinguish them from the first experimental ones, and allowed ...

New Delhi: Each DNA strand is made of 4 chemical units called nucleotide bases which compromise the GENETIC ALPHABET. These bases are Adenine(A), Guanine (G), Cytosine(C), and Thymine(T). The sequence ...

Genotypic testing is recommended as the preferred resistance testing method to guide therapy in antiretroviral-naive and antiretroviral-experienced persons. A major limitation of clinically available ...