Two cells in a tissue or a cell culture are never exactly identical, even if they share the same genetic heritage and microenvironment. This heterogeneity can be a consequence of differences in age, ...

SIMIP enables high-resolution images rich in both chemical and spatial information. A quantum cascade laser (QCL) excites molecular vibrations while a spatial light modulator (SLM) generates striped ...

Researchers have developed a new microscope that can visualize the optical response of surfaces at an unprecedented spatial resolution of one nanometer. This paves the way for optical microscopy of ...

Photoluminescence (PL) describes the process of light absorption and subsequent re-emission by a material and its characterization is a powerful tool for unveiling the optical and electronic ...

Bioengineers bridge the gap between spectroscopy developers and biologists through a systematic guide explaining modern Raman ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues at the frontier of biological research. Professor Xi Peng's group at ...

Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and ...

Understanding the interaction between light and matter at the smallest scales (angstrom scale) is essential for advancing technology and materials science. Atomic-scale structures, such as defects in ...

As a researcher interested in the architecture and organization of neurons within mammalian brains, Christophe Leterrier, a neuroscientist at the French National Centre for Scientific Research-Aix ...

More than 400 years have already passed since human beings invented the microscope, a technique for observing the microscopic world. The exploration of microscopic world using microscopes has been the ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...