Polychlorinated biphenyls (PCBs) are highly stable synthetic organic compounds that are present in air, water, and soil. PCBs have been identified in post-mortem human brains, indicating a possible ...

Depression is a leading contributor to the global disability burden, with high lifetime prevalence, elevated risk of suicide, and critically increasing incidence [1]. Selective Serotonin Reuptake ...

A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular ...

The heart and brain are among the earliest and most metabolically demanding organs in human development. Though historically studied in isolation, both ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Salk researchers used spatial transcriptomics to map where different cell types reside in the mouse brain. Shown are excitatory neurons (left, blue), inhibitory neurons (middle, red), and non-neuronal ...