eLife

Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface

An AI-driven computational toolkit, Gcoupler, integrates ligand design, statistical modeling, and graph neural networks to predict endogenous metabolites that allosterically modulate the GPCR–Gα ...
Scientific Research Publishing

BIM Applied to Bridges: Single-Cell Box Deck Modelling Supported by Dynamo Programming ()

Sampaio, A. , Figueiras, J. and Gomes, A. (2025) BIM Applied to Bridges: Single-Cell Box Deck Modelling Supported by Dynamo ...
eLife

Evolutionary remodeling of non-canonical ORF translation in mammals

This study presents a large, systematically curated catalog of non-canonical open reading frames (ncORFs) in human and mouse by reanalyzing nearly 400 Ribo-seq datasets using a standardized pipeline; ...